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Upstream Processing
Upstream Processing
Upstream Processing is a range of sophisticated systems catering to clarification & purification of biological process fluids. These systems are available as completely automated / semi-automatic / manual-based with scalability to match individual requirement and a host of customer-friendly features like Sanitization & SIP as per cGMP guidelines. The unit is backed by comprehensive documentation to support validation requirements.
Principle Involved
The system operates on the principle of depth filtration techniques that remove contaminants in Fermenter Feed System, based on mechanical removal and electrokinetic adsorption. The system incorporates CUNO Zeta plus filter of various grades which are designed for specific applications.
- Pre-filtration of growth media nutrients, make up water, raw materials, etc.
- Bio-reduction & clarification of Sera, reagents & buffers.
- Clarification of serum.
- Reduction of contaminating viruses from Serum based media.
- Sterile vent for holding & mixing tanks.
- Sterile filtration of air & nitrogen.
- Sterile filtration of serum and media.
- Steam filtration.
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Poly Tetra Fluoro Ethylene Membrane Filter Cartridges
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Stainless Steel Sintered Powder Filter Cartridges
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Polygon Turning Machine - TPT-5S, TPT-5ST
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