Sterile Liquid Filler

Sterile Liquid Filler


Industrial & Commercial Enterprises (INCOME) offers the new Macofar LF 200 Sterile Liquid Filler manufactured by Romaco, Germany, for high-speed filling of sterile pharmaceutical liquids. High-speed machines that combine maximum product safety with extreme flexibility are in demand when it comes to filling sterile pharmaceutical liquids into vials. The Macofar LF 200 ST aseptic liquid filler meets these challenges. It is capable of processing injection vials and infusion bottles with an unusually wide range of filling volumes from 0.5 to 500 ml. The maximum filling speed of 12,000 vials an hour is achieved with volumes up to five ml. The machine complies with the rigorous cGMP requirements for processing sterile, parenteral pharmaceutical liquids. The balcony structure of the Macofar LF 200 ST facilitates a strict separation between the “white” (cleanroom) and “grey” (technical) areas. The critical area passed through by the open vials is very narrow and compact. The slim design of this area guarantees excellent sterility assurance levels (SAL). A vertical laminar flow prevents turbulent air movements in the vicinity of the open vials and stops particles and microorganisms from developing. The bottom-up filling process is intermittent and involves eight servo-driven rotary piston pumps. Once filled, the glass or plastic vials are sealed with a rubber stopper and aluminium cap. The Macofar closing system is also suitable for subsequent freeze drying. The time required to clean and retool this compact machine is comparatively short. The liquid filler consequently unites maximum product safety and quality with outstanding value for money. If desired, the Macofar LF 200 ST can be hooked up to an upstream sterile washing machine, a depyrogenation tunnel and a downstream Promatic cartoner to obtain a complete liquid filling line. The compatibility and system expertise of Romaco’s Macofar and Promatic brands thus generate several key benefits for users.

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